MASTERMIND API

All of the Power of the Mastermind Genomic Search Engine - Automated.

The Mastermind API

Mastermind offers a Base API and Advanced API for integrating insight from the genomic medical literature into your platform or automated genomic analysis pipeline.

View the full API documentation here

API Demo

Try the interactive demo below, powered by the Mastermind API.

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Suggestions Endpoint Base API

Returns the canonical name(s) to query in Mastermind for the given disease, gene, or variant.

See the full API documentation linked above for details and information about each of the input filters below, including acceptable values, formatting, etc.

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API Results

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Response

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Counts Endpoint Base API

Returns the number of articles that match the given query.

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Response

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Articles Endpoint Advanced API

Returns the list of articles, ranked by relevance, for the given query.

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Response

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Diseases Endpoint Advanced API

Returns the top 5 diseases, ranked by number of matched articles, for the given query.

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Request

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Response

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Phenotypes Endpoint Advanced API

This endpoint is in beta and may change before it's finalized.
Returns the top 5 phenotypes, ranked by number of matched articles, for the given query.

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Request

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Response

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Therapies Endpoint Advanced API

This endpoint is in beta and may change before it's finalized.
Returns the top 5 therapies, ranked by number of matched articles, for the given query.

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Request

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Response

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Genes Endpoint Advanced API

Returns the top 5 genes, ranked by number of matched articles, for the given query.

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Request

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Response

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Variants Endpoint Advanced API

Returns the top 5 variants, ranked by number of matched articles, for the given query.

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Request

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Response

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CNVs Endpoint Advanced API

Returns the top 5 CNVs, ranked by number of matched articles, for the given query.

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Request

API URL:
Example usage:

Response

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Body:
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Article Info Endpoint Advanced API

Returns the matched diseases, genes, variants, and article meta-data for the given article PMID.

See the full API documentation linked above for details and information about each of the input filters below, including acceptable values, formatting, etc.

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Try this PMID, for example: 23543365

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Request

API URL:
Example usage:

Response

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Body:
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"File Annotation Counts" Endpoint Advanced API

Returns an annotated VCF from an input VCF file containing multiple variants as genomic coordinates with each variant in the output file annotated with the number of articles and Mastermind URL for each variant.

Easily integrate evidence from Mastermind into your existing genomics pipeline. Use the API to upload a VCF file, and get automatic annotations from Mastermind.

Mastermind VCF Annotations add annotations to variants containing the nubmer of publications which cite evidence for the variant, along with a URL to investigate the evidence.

Two annotations are added to each variant within the VCF file which contains evidence found by Mastermind in the medical literature:

  1. MMCNT: The number of articles found for this variant.
  2. MMURI: The Mastermind URL to view and investigate the matched articles.

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View the full API documentation here